Prepare Venison: Trim any fat from the venison and slice it into thin, even strips.
Make Marinade: In a bowl, combine soy sauce, Worcestershire sauce, brown sugar, apple cider vinegar, minced garlic, onion powder, smoked paprika, black pepper, and red pepper flakes.
Marinate: Place the venison strips in the marinade, ensuring they are fully covered. Marinate in the refrigerator for at least 4 hours, preferably overnight.
Dry Venison: Preheat your oven to 160°F (70°C). Remove the venison from the marinade and pat dry with paper towels. Arrange the strips on a wire rack over a baking sheet.
Oven Drying: Bake for 4 to 6 hours, or until the jerky is dry and slightly pliable.
Cool and Store: Let the jerky cool completely before storing in an airtight container.