Prepare the Marinade: In a large bowl, mix together soy sauce, Worcestershire sauce, hot sauce, apple cider vinegar, minced garlic, smoked paprika, chili powder, cayenne pepper, onion powder, and black pepper.
Marinate the Beef: Place the beef slices in a resealable bag and pour the marinade over them. Ensure all pieces are well-coated. Seal and refrigerate for at least 4 hours, preferably overnight.
Dry the Beef: Preheat your oven to 175°F (80°C). Take the beef out of the marinade, gently pat dry with paper towels, and arrange the slices on a wire rack over a baking sheet.
Bake: Bake in the preheated oven for 3-4 hours, or until the beef is dried to your preference.
Cool and Store: Let the jerky cool completely before storing in an airtight container. It can be kept in a cool, dry place for up to 2 weeks.
Preparation Time: 20 minutes