Start by slicing the venison into thin, even strips.
In a bowl, mix together bourbon, brown sugar, soy sauce, Worcestershire sauce, garlic powder, onion powder, black pepper, cayenne pepper, and liquid smoke.
Place venison strips in a large ziplock bag, pour in the marinade, and ensure they are well coated. Marinate in the refrigerator for at least 4 hours, preferably overnight.
Preheat your dehydrator to 160°F (71°C).
Arrange the marinated venison strips on the dehydrator trays, ensuring they do not touch or overlap.
Dehydrate for 4-6 hours, or until the jerky is dry but still pliable.
Let the jerky cool before storing in an airtight container.